Endocrine Abstracts

Introduction: Adiponectin (AdipoQ) is a known insulinsensitizing adipokine which is also present in fetal circulation. It has been postulated to play a role in the regulation of fetal growth and development together with other adipokines. The aim of the study was to determine fetal adiponectin and find its correlations with the neonatal birthweight and maternal AdipoQ.Patients and methods: The study included 36 women with singleton pregnancy (20 diagnose...

Introduction: The course of type 2 diabetes (DM2) is linked with increased fibroblast growth factor 21 (FGF21) concentrations, however little information is available on the prognostic significance of FGF21 in DM2. The aim of the study was to assess whether FGF21 may be a predictor of cardiovascular (CV) events in patients with DM2.Patients and methods: The study comprised 87 patients with DM2, aged 57–66 years, with the median duration of diabetes ...

Introduction: Adiponectin shows its beneficial insulin-sensitizing properties, however, women with gestational diabetes mellitus (GDM) present hypoadiponectinemia.Aim of the study: To assess the expression of adiponectin gene as well as its AdipoR1 and AdipoR2 receptors in placenta and adipose tissue and to determine potential correlations with chosen metabolic parameters (clinical and biochemical).Patients and methods: Thirty-six ...

Introduction: The patients with ACS and scheduled for an elective coronary angiography have high frequency of both newly and previously diagnosed diabetes. The diabetic patients with acute myocardial infarction have an increased risk of death. Elevated blood HYC is strongly related to an increased risk for atherosclerosis and cardiovascular disease. This association is particularly evident in patients with diabetes.Aim of the study: An attempt to evaluat...